S. Jackson点评道：
原文： I'm really surprised that people are rating this product with 5 stars? Maybe some people are receiving the placebo effect, are super sensitive or perhaps its just the relativity (i.e., some curcumin, even if just a little, is better than no curcumin) or a combo of these? For those who did & did not
receive a therapeutic effect from this supplement, or from ingesting the turmeric spice, read on to find out why.
Ok, so YES, turmeric/curcumin is excellent for so many things - its an anti-inflammatory, anti-depressant, anti-anxiety, resolves many mental health issues resulting from low serotonin, dopamine & melatonin, helps against pro-inflammatory diseases including cancer, cardiovascular disease, arthritis, uveitis, ulcerative proctitis, Crohn’s disease, ulcerative colitis, irritable bowel disease, tropical pancreatitis, peptic ulcer, gastric ulcer, idiopathic orbital inflammatory pseudotumor, oral lichen planus, gastric inflammation, vitiligo, psoriasis, acute coronary syndrome, atherosclerosis, diabetes, diabetic nephropathy, diabetic microangiopathy, lupus nephritis, renal conditions, acquired immunodeficiency syndrome, '-thalassemia, biliary dyskinesia, Dejerine-Sottas disease, cholecystitis, and chronic bacterial prostatitis.
HOWEVER, in order to absorb this wonderful, miracle spice-compound, you have to have an additive, such as bioperine to improve its bioavailability, as curcumin has very poor absorption rates, rapid metabolism & rapid systemic elimination rates. There is nothing in this product that increases curcumin's bioavailability. Therefore, for those who take this, or any other turmeric/curcumin supplement that doesn't have a compound designed to increase bioavailability, like an adjuvant, or for those who try to eat the spice to obtain its healthy effects, unfortunately, you are barely getting any true therapeutic effect (if any).
According to the NIH, the use of adjuvants that can block the metabolic pathway of curcumin is the most common strategy for increasing the bioavailability of curcumin. The effect of combining piperine [found in bioperine], a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavailability of curcumin in healthy human volunteers. In humans receiving a dose of 2g of curcumin alone, serum levels of curcumin were either undetectable or very low. Concomitant administration of 20mg of piperine with curcumin, however, produced much higher concentrations within 30 min to 1 h after drug treatment; piperine increased the bioavailability of curcumin by 2,000%. You can read the study here, but if you Google it, you will find that there are numerous scientific studies confirming these facts: [...]
SO, if you felt like you received a therapeutic effect from this non-bioavailable supplement, imagine how you will feel when you absorb 2000% more?! If you have to stick with this supplement, then at least add bioperine (can purchase separately). For me, I don't like taking so many pills, so I prefer to purchase Curcumin with BioPerine already in it at the appropriate doses. Many are available on Amazon (I like Purely Holistic), but don't let the $24 price throw you off, as it is a 4 month supply, so that's $6/month (many are around this price, but some are about $16 or so). If you compare the two options, when you have to purchase bioperine separately, its about $8 (range is $4 - $20) + almost $7 for this supplement, for a 2-month supply. So, you can do the math & figure out that this supplement is actually more expensive than the good, organic brands! Hope this helps! :)
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译文：
我真的很惊讶人们给了这个产品5星级评价。也许有些人是在自我安慰，也可能只是相对而言（也就是说，有一些姜黄素，哪怕只是一点点，也比没有姜黄素更好），我给出的是中肯的评价，我觉得这个药没有治疗效果，看下面我给的原因。
是的，姜黄素的确是好东西，它可以抗炎、抗抑郁、抗焦虑，解决了许多心理健康问题，低血清素，多巴胺，褪黑素，有助于对避免炎性疾病包括癌症、心血管疾病、关节炎、葡萄膜炎、溃疡性直肠炎、Crohn氏病、溃疡性结肠炎、肠易激综合症、热带胰腺炎、消化性溃疡、胃溃疡、特发性眼眶炎性假瘤、口腔扁平苔藓、胃炎、白癜风、银屑病、急性冠脉综合征，动脉硬化，糖尿病，糖尿病肾病，糖尿病微血管病变，狼疮性肾炎。在肾功能正常的条件下，降低衍生成为免疫缺陷综合征，地中海贫血、胆红素气的运动障碍，Dejerine Sottas病，胆囊炎，慢性细菌性前列腺炎。
然而，为了吸收这奇迹般的香料化合物，你必须有添加剂，如用Bioperine来提高其生物利用度，curcumin的吸收率很差，代谢很快；很快就会在体内消失。该产品没有增加姜黄素。因此，对于那些服用这种药物，或者任何其他姜黄姜黄素补充剂的人，都需要有一种能增加生物利用度的化合物，如一种佐剂，或者那些试图食用香料以获得健康效果的化合物，不幸的是，你几乎得不到任何真正的治疗效果。
根据美国国家卫生研究院的研究，使用能够阻断姜黄素代谢途径的佐剂是提高姜黄素生物利用度的最常用策略。在人类接受使用剂量为2毫克的姜黄素时，血清中姜黄素含量将不可检测或非常低。同时服用胡椒碱与姜黄素20mg，会在药物治疗后的30分钟到1小时里产生更高的浓度；胡椒碱增加姜黄素的生物利用度2，000%。你可以在这里阅读研究，但如果你用谷歌，你会发现有许多科学研究证实了这些事实：……
所以，如果你觉得你收到的治疗效果是可利用非生物的补充，你觉得你吸收的2000%多吗？！如果你要坚持用这个补充，那么至少再买一样Bioperine（可单独购买）。对我来说，我不喜欢带这么多药，所以我更喜欢购买姜黄素Bioperine，这已经足够了。亚马逊上有很多，但不要被24美元的价格欺骗，因为它是一瓶可以4个月的供应，所以大概6美元一个月（一般是这个价格，但有些是大约16美元左右）。比较这两个选项，单独购买Bioperine，大约8美元（范围是4美元至20美元）。所以，你可以自己算一下怎么才是最划算的。希望我的建议会对你们这有帮助！
